Canada is the first of the G-7 countries to authorize generic semaglutide, the active ingredient in Novo Nordisk's Ozempic
Its important because vitamin B12 is integral for many functions, including optimized cell reproduction, blood formation, protein, and tissue synthesis
The most cited single result is from Yun and colleagues in 2018, who showed that NLY01, a long-acting PEGylated GLP-1R agonist, blocked the microglia-driven conversion of resting astrocytes into the neurotoxic A1 phenotype in mouse models, a process implicated in neuronal death in both Parkinsons and Alzheimers disease [4]
Neuroprotective Effects: Both peptides have shown potential in protecting brain cells from various types of damage, thereby supporting long-term cognitive health
This process typically takes 15 to 20 minutes
If these cells remain sequestered at the capsular bag periphery, this could contribute to Soemmerings ring expansion, but that would be expected to occur only slowly due to a contact inhibition directed brake on cell proliferation (83)